Polyclonal Anti- CD24 antibody

Catalog# YPA1272

Lot # Check on the product label

Size 100 μl

Isotype IgG

Host Rabbit

Reactivity 

Human

Immunogen Synthetic peptide within Human CD24 aa 1-50 / 80.

Purification Immunogen affinity purified

Content 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Recommend Application

Western Blot, WB (1:250-1:1000)

Immunohistochemistry, IHC (1:20-1:100)

Other applications have not been tested.

The optimal dilutions should be determined  by end user.

Storage Instruction 

Ship at 2-8°C, when receipt, aliquot and store at -20°C for one year.

Avoid repeated freeze and thaw cycles.

Background

Signal transducer CD24, also known as cluster of differentiation 24 or heat stable antigen CD24 (HSA), is a protein that in humans is encoded by the CD24 gene. This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and B cells and modulates growth and differentiation signals to these cells. The precursor protein is cleaved to a short 32 amino acid mature peptide which is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface. This gene was missing from previous genome assemblies, but is properly located on chromosome 6. Non-transcribed pseudogenes have been designated on chromosomes 1, 15, 20, and Y. Alternative splicing results in multiple transcript variants.

Reference

1. Gilliam, Daniel T.; Menon, Vishal; Bretz, Niko P.; Pruszak, Jan. "The CD24 surface antigen in neural development and disease". Neurobiology of Disease. 99: 133–144.

2. Hough MR, Rosten PM, Sexton TL, Kay R, Humphries RK (July 1994). "Mapping of CD24 and homologous sequences to multiple chromosomal loci". Genomics. 22 (1): 154–61.