APC anti-human CD3 antibody
|
Catalog# |
BFA1002-2 |
|---|---|
|
Lot # |
Check on the product label |
|
Size |
50 Tests |
| Isotype | Mouse IgG1,κ |
| Clone # | 3H1 |
| Host |
Mouse |
| Reactivity | Human |
|
Purification |
Affinity purified |
| Content | 0.01M PBS, pH 7.4, 0.2%BSA, 0.1% ProClin300. |
| Recommend Application | Flow Cytometry, Flow-Cyt (5 μl/test) Other applications have not been tested. The optimal dilutions should be determined by end user. |
| Storage Instruction | Ship at 2-8°C, when receipt, aliquot and store at 2-8°C in dark for one year. Do not freeze. Avoid repeated freeze and thaw cycles. |
|
Background |
CD3 (cluster of differentiation 3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell (CD8+ naive T cells) and T helper cells (CD4+ naive T cells). It is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These chains associate with the T-cell receptor (TCR) and the CD3-zeta (ζ-chain) to generate an activation signal in T lymphocytes. The TCR, CD3-zeta, and the other CD3 molecules together constitute the TCR complex. |
|
Reference |
1. Yang H, Parkhouse RM, Wileman T (June 2005). "Monoclonal antibodies that identify the CD3 molecules expressed specifically at the surface of porcine gammadelta-T cells". Immunology. 115 (2): 189–196. |
