Apolipoprotein B, Apo B Protein (Active)

Catalog# BNP1002-2

Lot # Check on the product label

Size 1 mg

Description

Purified human Apolipoprotein B protein.

Source Human serum

Purity >90% by SDS-PAGE

Formulation Liquid

Application

ELISA

Other applications have not been tested.

The optimal dilutions should be determined by end user.

Storage buffer

Each vial contains 10mM PBS (pH7.4).

Storage & Expiration

Ship at 4℃. Upon receipt, aliquot and store at -20℃ or -80℃ for long term.

Avoid repeated freeze and thaw cycles.

Background

Apolipoprotein B (ApoB) are the primary apolipoproteins of chylomicrons and low-density lipoproteins(LDL), which is responsible for carrying cholesterol to tissues. It is the primary apolipoprotein component, acts as a ligand for LDL receptors in various cells throughout the body. Through a mechanism that is not fully understood, high levels of ApoB can lead to plaques that cause vascular disease (atherosclerosis), leading to heart disease, the levels of ApoB are a better indicator of heart disease risk than total cholesterol or LDL.

Reference

1. Contois JH, Warnick GR, Sniderman AD (2011). "Reliability of low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol, and apolipoprotein B measurement". JOURNAL OF CLINICAL LIPIDOLOGY 5 (4): 264–272.