Apolipoprotein A, Apo A Protein (Active)

Catalog# BNP1001-2

Lot # Check on the product label

Size 1 mg

Description

Purified human Apolipoprotein A protein.

Source Human serum

Purity >90% by SDS-PAGE

Formulation Liquid

Application

ELISA

Other applications have not been tested.

The optimal dilutions should be determined by end user.

Storage buffer

Each vial contains 10 mM PBS (pH7.4).

Storage & Expiration

Ship at 4℃. Upon receipt, aliquot and store at -20℃ or -80℃ for long term.

Avoid repeated freeze and thaw cycles.

Background

Apolipoproteins are proteins that bind lipids (oil-soluble substances such as fat and cholesterol) to form lipoproteins. They transport the lipids through the lymphatic and circulatory systems. They transport the lipids through the lymphatic and circulatory systems. Apoprotein A is one of exchangeable apolipoproteins which have the same genomic structure and are members of a multi-gene family that probably evolved from a common ancestral gene. ApoA1 and ApoA4 are part of the APOA1/C3/A4/A5 gene cluster on chromosome 11. They are consist of alpha-helices and associate with lipid droplets reversibly.

Reference

1. Saito H, Lund-Katz S, Phillips MC (July 2004). "Contributions of domain structure and lipid interaction to the functionality of exchangeable human apolipoproteins". Prog. Lipid Res. 43 (4): 350–80.

2. Wilson C, Wardell MR, Weisgraber KH, Mahley RW, Agard DA; Wardell; Weisgraber; Mahley; Agard (June 1991). "Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein E". Science 252 (5014): 1817–22.