Recombinant Human GM-CSF Protein

Check on the product label

50 μg

Recombinant human GM-CSF is produced by the E.coli system, with the target gene encoding Ala18-Glu144 expressed.

CSF2, GMCSF, colony stimulating factor 2, CSF

E.coli

P04141

>95% by SDS-PAGE

<0.01 EU/µg by LAL test

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Dissolve the lyophilized protein in distilled water (It is not recommended to reconstitute to a concentration <100 μg/ml.)

SDS-PAGE

Other applications have not been tested.

The optimal dilutions should be determined by end user.

Ship at 4℃. Upon receipt, aliquot and store at -20℃ or -80℃ for long term.

Avoid repeated freeze and thaw cycles.

Granulocyte-macrophage colony- stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, natural killer cells, endothelial cells and fibroblasts that functions as a cytokine. The pharmaceutical analogs of naturally occurring GM-CSF are called sargramostim and molgramostim. Unlike granulocyte colony-stimulating factor, which specifically promotes neutrophil proliferation and maturation, GM-CSF affects more cell types, especially macrophages and eosinophils.

1. Root RK, Dale DC (March 1999). "Granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor: comparisons and potential for use in the treatment of infections in nonneutropenic patients". The Journal of Infectious Diseases. 179 (Suppl 2): S342-52.