Recombinant SARS-CoV-2 Nucleocapsid Protein (Omicron-BA.2)

Catalog# BRP1150

Lot # Check on the product label

Size 1 mg

Description

Recombinant SARS-CoV-2 Nucleocapsid Protein (Omicron-BA.2) with his tag.

Source E.coli

Purity >95% by SDS-PAGE

Molecular Weight 47kDa

Formulation Liquid

Application

Western Blot

ELISA

Other applications have not been tested.

The optimal dilutions should be determined by end user.

Storage buffer

0.01M PBS, 0.3M NaCl pH7.0, 0.1% Proclin300.

Storage & Expiration

Ship at 4℃. Upon receipt, aliquot and store at -20℃ for long term.

Avoid repeated freeze and thaw cycles.

Background

Omicron (BA.2), is not only more transmissible than BA.1, may cause more severe disease. BA.1 has itself been divided in two, the original BA.1 and BA.1.1 where the main difference is that the latter has a R346K mutation. A notable difference between the BA.1 and BA.2 is that the latter lacks the characteristic S-gene target failure (SGTF) causing deletion (Δ69-70) by which many qPCR tests are able to rapidly detect a case as an Omicron (or Alpha) variant, from the previously dominant Delta variant.

Reference

1. Vauhkonen H, Nguyen PT, Kant R, Plyusnin I, Erdin M, Kurkela S, et al. (June 2022). "Introduction and Rapid Spread of SARS-CoV-2 Omicron Variant and Dynamics of BA.1 and BA.1.1 Sublineages, Finland, December 2021". Emerging Infectious Diseases. 28 (6): 1229–1232.

2. Yamasoba D, Kimura I, Nasser H, Morioka Y, Nao N, Ito J, et al. (15 February 2022). "Virological characteristics of SARS-CoV-2 BA.2 variant". bioRxiv.

3. "Stealth Omicron: What is The Fast Spreading Omicron BA.2 Sub-Variant That Can Escape RT-PCR Test". india.com. 23 January 2022. Archived from the original on 23 January 2022. Retrieved 23 January 2022.